Distinct monocyte subset phenotypes in patients with different clinical forms of chronic Chagas disease and seronegative dilated cardiomyopathy.

• Main Authors: Damián E Pérez-Mazliah (Author), Melisa D Castro Eiro (Author), María Gabriela Álvarez (Author), Bruno Lococo (Author), Graciela Bertocchi (Author), Gonzalo César (Author), María A Natale (Author), María C Albareda (Author), Rodolfo Viotti (Author), Susana A Laucella (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Chronic infection with Trypanosoma cruzi leads to a constant stimulation of the host immune system. Monocytes, which are recruited in response to inflammatory signals, are divided into classical CD14hiCD16-, non-classical CD14loCD16+ and intermediate CD14hiCD16+ subsets. In this study, we...