Development of Inhalable Spray Dried Nitrofurantoin Formulations for the Treatment of Emphysema

• Main Authors: Mathew N. Leslie (Author), Nirmal Marasini (Author), Zara Sheikh (Author), Paul M. Young (Author), Daniela Traini (Author), Hui Xin Ong (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A central characteristic of emphysematous progression is the continuous destruction of the lung extracellular matrix (ECM). Current treatments for emphysema have only addressed symptoms rather than preventing or reversing the loss of lung ECM. Nitrofurantoin (NF) is an antibiotic that has the potent...