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Protective Effects of Sacubitril/Valsartan on Cardiac Fibrosis and Function in Rats With Experimental Myocardial Infarction Involves Inhibition of Collagen Synthesis by Myocardial Fibroblasts Through Downregulating TGF-β1/Smads Pathway

Objectives: To investigate the effect and mechanism of sacubitril/valsartan on myocardial fibrosis in rats following experimental myocardial infarction and in TGF-β1-treated myocardial fibroblasts.Methods: Male Sprague-Dawley (SD) rats were subjected to coronary artery ligation to establish myocardi...

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में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Meifang Wu (लेखक), Yanguang Guo (लेखक), Ying Wu (लेखक), Kaizu Xu (लेखक), Liming Lin (लेखक)
स्वरूप: पुस्तक
प्रकाशित: Frontiers Media S.A., 2021-05-01T00:00:00Z.
विषय:
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