In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells

Virus-based gene therapy by CRISPR/Cas9-mediated genome editing and knockout may provide a new option for treatment of inherited and acquired ocular diseases of the retina. In support of this notion, we show that Streptococcus pyogenes (Sp) Cas9, delivered by lentiviral vectors (LVs), can be used in...

Full description

Saved in:
Bibliographic Details
Main Authors: Andreas Holmgaard (Author), Anne Louise Askou (Author), Josephine Natalia Esther Benckendorff (Author), Emil Aagaard Thomsen (Author), Yujia Cai (Author), Toke Bek (Author), Jacob Giehm Mikkelsen (Author), Thomas J. Corydon (Author)
Format: Book
Published: Elsevier, 2017-12-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items