Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B

• Main Authors: Sevilay Batıbay (Author), Duygu Geler Külcü (Author), Nilgün Mesci (Author), Borçak Çağlar Ruhi (Author), Zerrin Şahin (Author), Hasan Gündoğdu (Author)
• Format: Book
• Published: Galenos Yayinevi, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adefovir dipivoxil (ADV) is a nucleotide analogue used in the chronic hepatitis B treatment. Proximal renal tubular dysfunction is one of the adverse effects of this agent and characterized with hypophosphatemia and osteomalacia. However, reduced bone mineral density with fracture due to ADV therapy...