Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease

• Main Authors: Ke Mo (Author), Yongli Chu (Author), Yang Liu (Author), Guibin Zheng (Author), Kaiyu Song (Author), Qiong Song (Author), Haitao Zheng (Author), Yuxiao Tang (Author), Xinghan Tian (Author), Wenjie Yao (Author), Han Fang (Author), Kejian Wang (Author), Yongqiang Jiang (Author), Dengfeng Yang (Author), Yixuan Chen (Author), Chengyu Huang (Author), Ting Li (Author), Hongmei Qu (Author), Xicheng Song (Author), Jin Zhou (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Both environmental and genetic factors contribute to the etiology of autoimmune thyroid disease (AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT). However, the exact pathogenesis and interactions that occur between environmental factors and genes remain unclear, and th...