Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues

• Main Authors: Anusha Balla (Author), Seppo Auriola (Author), Angus C. Grey (Author), Nicholas J. Demarais (Author), Annika Valtari (Author), Emma M. Heikkinen (Author), Elisa Toropainen (Author), Arto Urtti (Author), Kati-Sisko Vellonen (Author), Marika Ruponen (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ocular drug absorption after eye drop instillation has been widely studied, but partitioning phenomena and spatial drug distribution are poorly understood. We investigated partitioning of seven beta-blocking drugs in corneal epithelium, corneal stroma, including endothelium and conjunctiva, using is...