Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer

• Main Authors: Justyna Magdalena Hermanowicz (Author), Anna Szymanowska (Author), Beata Sieklucka (Author), Robert Czarnomysy (Author), Krystyna Pawlak (Author), Anna Bielawska (Author), Krzysztof Bielawski (Author), Joanna Kalafut (Author), Alicja Przybyszewska (Author), Arkadiusz Surazynski (Author), Adolfo Rivero-Muller (Author), Mariusz Mojzych (Author), Dariusz Pawlak (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in men and in women. The impact of the new pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide (MM-129) was evaluated against human colon cancer in vitro and in zebrafish xenografts. Our results show that this new sy...