Safety of Inclisiran: A Disproportionality Analysis from the EudraVigilance Database

• Main Authors: Giuseppe Cicala (Author), Michelangelo Rottura (Author), Viviana Maria Gianguzzo (Author), Federica Cristiano (Author), Selene Francesca Anna Drago (Author), Giovanni Pallio (Author), Natasha Irrera (Author), Egidio Imbalzano (Author), Edoardo Spina (Author), Vincenzo Arcoraci (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Introduction:</b> The discovery of serine protease proprotein convertase subtilisin-kexin type 9 (PCSK9) has revolutionized pharmacological lipid-lowering treatments. The first PCSK9 antagonists (PCSK9-A), evolocumab and alirocumab, were approved in 2015. Targeting PCSK9 synthesis mar...