Rapamycin-Loaded Polymeric Nanoparticles as an Advanced Formulation for Macrophage Targeting in Atherosclerosis

• Main Authors: Emanuela Fabiola Craparo (Author), Marta Cabibbo (Author), Alice Conigliaro (Author), Maria Magdalena Barreca (Author), Teresa Musumeci (Author), Gaetano Giammona (Author), Gennara Cavallaro (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, rapamycin (Rapa) represents a potential drug treatment to induce regression of atherosclerotic plaques; however, its use requires site-specific accumulation in the vessels involved in the formation of the plaques to avoid the systemic effects resulting from its indiscriminate biodistributi...