PMS2 gene mutation results in DNA mismatch repair system failure in a case of adult granulosa cell tumor

• Päätekijät: Wen-Chung Wang (Tekijä), Ya-Ting Lee (Tekijä), Yen-Chein Lai (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2017-03-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecular studies have characterized the FOXL2 402C > G mutation in adult...