Cell-type-specific alternative polyadenylation promotes oncogenic gene expression in non-small cell lung cancer progression

• Autori principali: Kexin Huang (Autore), Yun Zhang (Autore), Xiaorui Shi (Autore), Zhiqin Yin (Autore), Weiling Zhao (Autore), Liyu Huang (Autore), Fu Wang (Autore), Xiaobo Zhou (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2023-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Disrupted alternative polyadenylation (APA) is frequently involved in tumorigenesis and cancer progression by regulating the gene expression of oncogenes and tumor suppressors. However, limited knowledge of tumor-type- and cell-type-specific APA events may lead to novel APA events and their function...