Super-enhancer-driven LncRNA PPARα-seRNA exacerbates glucolipid metabolism and diabetic cardiomyopathy via recruiting KDM4B

• Glavni autori: Xiaozhu Ma (Autor), Shuai Mei (Autor), Qidamugai Wuyun (Autor), Li Zhou (Autor), Ziyang Cai (Autor), Hu Ding (Autor), Jiangtao Yan (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2024-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objective: Aberrant glucolipid metabolism in the heart is a characteristic factor in diabetic cardiomyopathy (DbCM). Super-enhancers-driven noncoding RNAs (seRNAs) are emerging as powerful regulators in the progression of cardiac diseases. However, the functions of seRNAs in DbCM have not been fully...