High Mobility Group Box 1 Protein Induction by Mycobacterium Bovis BCG

• Main Authors: Péter Hofner (Author), György Seprényi (Author), András Miczák (Author), Krisztina Buzás (Author), Zsófia Gyulai (Author), Katalin F. Medzihradszky (Author), Ari Rouhiainen (Author), Heikki Rauvala (Author), Yvette Mándi (Author)
• Format: Book
• Published: Hindawi Limited, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High mobility group box 1 protein (HMGB1), a nuclear protein, is a critical cytokine that mediates the response to infection, injury, and inflammation. The aim of our study was to elaborate a reliable in vitro model to investigate whether Mycobacterium bovis BCG is able to induce HMGB1 secretion fro...