Metformin Modulates High Glucose-Incubated Human Umbilical Vein Endothelial Cells Proliferation and Apoptosis Through AMPK/CREB/BDNF Pathway

• Hoofdauteurs: Xiqiong Han (Auteur), Bilei Wang (Auteur), Yuning Sun (Auteur), Jia Huang (Auteur), Xin Wang (Auteur), Wenqi Ma (Auteur), Yi Zhu (Auteur), Rongfeng Xu (Auteur), Hong Jin (Auteur), Naifeng Liu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Cardiovascular disease (CVD) is a leading cause of mortality and morbidity among patients with diabetes. Endothelial dysfunction is an early physiological event in CVD. Metformin, a common oral antihyperglycemic agent, has been demonstrated to directly affect endothelial cell function. Brain-derived...