Metformin Modulates High Glucose-Incubated Human Umbilical Vein Endothelial Cells Proliferation and Apoptosis Through AMPK/CREB/BDNF Pathway

Metformin Modulates High Glucose-Incubated Human Umbilical Vein Endothelial Cells Proliferation and Apoptosis Through AMPK/CREB/BDNF Pathway

Cardiovascular disease (CVD) is a leading cause of mortality and morbidity among patients with diabetes. Endothelial dysfunction is an early physiological event in CVD. Metformin, a common oral antihyperglycemic agent, has been demonstrated to directly affect endothelial cell function. Brain-derived...

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Main Authors: Xiqiong Han (Author), Bilei Wang (Author), Yuning Sun (Author), Jia Huang (Author), Xin Wang (Author), Wenqi Ma (Author), Yi Zhu (Author), Rongfeng Xu (Author), Hong Jin (Author), Naifeng Liu (Author)
Format: Book
Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
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