Integrated fecal microbiota and metabolomics analysis of the orlistat intervention effect on polycystic ovary syndrome rats induced by letrozole combined with a high-fat diet

• Hlavní autoři: Jianmei Yang (Autor), Enli Wang (Autor), Mingmin Jiang (Autor), Yujun Tan (Autor), Fangfang Yao (Autor), Chenghong Sun (Autor), Lihong Pan (Autor), Ling Gao (Autor), Jingchun Yao (Autor)
• Médium: Kniha
• Vydáno: BMC, 2023-06-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Background This study aimed to compare the characteristics of the gut microbiota and their metabolite profiles between polycystic ovary syndrome (PCOS) and orlistat-treated PCOS rats (ORL-PCOS), which could help to better understand the underlying mechanism of the effect of orlistat on PCOS...