Caspase Inhibition Augmented Oridonin-Induced Cell Death in Murine Fibrosarcoma L 929 by Enhancing Reactive Oxygen Species Generation

Oridonin, a diterpenoid isolated from Rabdosia rubescences, has been reported to have antitumor effects. In this study, the growth-inhibitory activity of oridonin for L929 cells was exerted in a time-and dose-dependent manner. After treatment with oridonin for 24 h, L929 cells underwent both apoptos...

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Main Authors: Jin-Nan Wu (Author), Jian Huang (Author), Jia Yang (Author), Shin-Ichi Tashiro (Author), Satoshi Onodera (Author), Takashi Ikejima (Author)
Format: Book
Published: Elsevier, 2008-01-01T00:00:00Z.
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