A picogram BA-ELISA quantification assay for rLj-RGD3, a platelet fibrinogen receptor antagonist, in the rat plasma and its application to a pharmacokinetic study.

• Main Authors: Yuping Wang (Author), Zhien Liu (Author), Guozhu Han (Author), Ping Yu (Author), Xiaobo Yang (Author), Jihong Wang (Author), Li Lv (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

rLj-RGD3, a new member of the RGD (Arginine-Glycine-Aspartate)-motif toxin protein family obtained from Lampetra japonica by means of recombinant DNA techniques, has been demonstrated to be a platelet fibrinogen receptor antagonist and holds potential as a drug candidate for a specific indication. T...