Tubeimoside 1 Acts as a Chemotherapeutic Synergist via Stimulating Macropinocytosis

• Main Authors: Xianling Gong (Author), Ruibo Sun (Author), Zhuowei Gao (Author), Weili Han (Author), Yawei Liu (Author), Liang Zhao (Author), Linlin Jing (Author), Xueqing Yao (Author), Xuegang Sun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macropinocytosis is a highly conserved endocytic process which characterizes the engulfment of extracellular fluid and its contents into cells via large, heterogeneous vacuoles known as macropinosomes. Tubeimoside-1 (TBM1) is a low toxic triterpenoid saponin extracted from a traditional Chinese herb...