E3 Ubiquitin Ligases: Potential Therapeutic Targets for Skeletal Pathology and Degeneration

• Main Authors: Ruiyin Zeng (Author), Yuan Xiong (Author), Ze Lin (Author), Adriana C. Panayi (Author), Yun Sun (Author), Faqi Cao (Author), Guohui Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ubiquitination-proteasome system (UPS) is crucial in regulating a variety of cellular processes including proliferation, differentiation, and survival. Ubiquitin protein ligase E3 is the most critical molecule in the UPS system. Dysregulation of the UPS system is associated with many conditions....