Lipid Adaptations against Oxidative Challenge in the Healthy Adult Human Brain

• Main Authors: Mariona Jové (Author), Natàlia Mota-Martorell (Author), Èlia Obis (Author), Joaquim Sol (Author), Meritxell Martín-Garí (Author), Isidre Ferrer (Author), Manuel Portero-Otín (Author), Reinald Pamplona (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It is assumed that the human brain is especially susceptible to oxidative stress, based on specific traits such as a higher rate of mitochondrial free radical production, a high content in peroxidizable fatty acids, and a low antioxidant defense. However, it is also evident that human neurons, altho...