Skeletal muscle hypertrophy rewires glucose metabolism: An experimental investigation and systematic review

• Main Authors: Philipp Baumert (Author), Sakari Mäntyselkä (Author), Martin Schönfelder (Author), Marie Heiber (Author), Mika Jos Jacobs (Author), Anandini Swaminathan (Author), Petras Minderis (Author), Mantas Dirmontas (Author), Karin Kleigrewe (Author), Chen Meng (Author), Michael Gigl (Author), Ildus I. Ahmetov (Author), Tomas Venckunas (Author), Hans Degens (Author), Aivaras Ratkevicius (Author), Juha J. Hulmi (Author), Henning Wackerhage (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Proliferating cancer cells shift their metabolism towards glycolysis, even in the presence of oxygen, to especially generate glycolytic intermediates as substrates for anabolic reactions. We hypothesize that a similar metabolic remodelling occurs during skeletal muscle hypertroph...