High-dose dextromethorphan produces myelinoid bodies in the hippocampus of rats

• 主要な著者: Hai-Quyen Tran (著者), Yoon Hee Chung (著者), Eun-Joo Shin (著者), Won Ki Kim (著者), Jae-Chul Lee (著者), Ji Hoon Jeong (著者), Myung Bok Wie (著者), Choon-Gon Jang (著者), Kiyofumi Yamada (著者), Toshitaka Nabeshima (著者), Hyoung-Chun Kim (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2016-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Dextromethorphan (DM) administered at supra-antitussive doses produce psychotoxic and neurotoxic effects in humans. We administered DM (80 mg/kg) to rats intraperitoneally to determine the ultrastructural change induced by DM, because intraperitoneal route is sensitive for the behavioral responses....