Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents

• Main Authors: Sudong Liang (Author), Yifei Geng (Author), Miao-Miao Niu (Author), Yan Zhang (Author), Weiping He (Author), Jindong Li (Author), Li Yang (Author), Zhen Xu (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Prostate cancer (PCa) is a clinically heterogeneous disease with a progressively increasing incidence. Concurrent inhibition of coactivator-associated arginine methyltransferase 1 (CARM1) and histone deacetylase 2 (HDAC2) could potentially be a novel strategy against PCa. Herein, we identified seven...