Disturbed Expression of EphB4, but Not EphrinB2, Inhibited Bone Regeneration in an In Vivo Inflammatory Microenvironment

• Main Authors: Li-Li Shen (Author), Li-Xia Zhang (Author), Li-Mei Wang (Author), Rong-Jing Zhou (Author), Cheng-Zhe Yang (Author), Jin Zhang (Author), Pi-Shan Yang (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The important role of ephrinB2-EphB4 signaling pathway in bone remodeling has been well established. However, it is still unclear whether this bidirectional signaling also has effects on the regenerative processes of bone defects created in an inflammatory microenvironment. In this study, an experim...