Reduced hydrogen sulfide production contributes to adrenal insufficiency induced by hypoxia via modulation of NLRP3 inflammasome activation

• Main Authors: Ningning Zhang (Author), Zhan Zhou (Author), Yan Huang (Author), Gang Wang (Author), Zhengshan Tang (Author), Jianqiang Lu (Author), Changnan Wang (Author), Xin Ni (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTObjective: Adrenocortical responsiveness is critical for maintaining glucocorticoids production and homeostasis during stress. We sought to investigate adrenocortical responsiveness during hypoxia in mice and the mechanisms responsible for the regulation of adrenal responsiveness.Methods: (1...