Effect of Coenzyme-Q10 on Doxorubicin-Induced Nephrotoxicity in Rats

• Ngā kaituhi matua: Azza A. K. El-Sheikh (Author), Mohamed A. Morsy (Author), Marwa M. Mahmoud (Author), Rehab A. Rifaai (Author), Aly M. Abdelrahman (Author)
• Hōputu: Pukapuka
• I whakaputaina: Hindawi Limited, 2012-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Nephrotoxicity is one of the limiting factors for using doxorubicin (Dox) as an anticancer chemotherapeutic. Here, we investigated possible protective effect of coenzyme-Q10 (CoQ10) on Dox-induced nephrotoxicity and the mechanisms involved. Two doses (10 and 100 mg/kg) of CoQ10 were administered ora...