Complex formation and functional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor

• Principais autores: Yuji Kamikubo (Autor), Toshihide Tabata (Autor), Hakushun Sakairi (Autor), Yoshie Hashimoto (Autor), Takashi Sakurai (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2015-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The adenosine A1 receptor (A1R) is a G protein-coupled receptor (GPCR) for adenosine, a ubiquitous neuromodulator, and thus regulates neuronal excitability, as well as arousal and sensitivity to pain. In addition, we have previously described a new mode of action for A1R: in cerebellar Purkinje cell...