Development, Characterization, and In Vivo Evaluation of a Novel Aptamer (Anti-MUC1/Y) for Breast Cancer Therapy

• मुख्य लेखकों: Huma Khan (लेखक), Vaidehi Makwana (लेखक), Sofia Nascimento dos Santos (लेखक), Carlos Eduardo Bonacossa de Almeida (लेखक), Ralph Santos-Oliveira (लेखक), Sotiris Missailidis (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by...