Population Pharmacokinetic Analysis for Imipenem-Relebactam in Healthy Volunteers and Patients With Bacterial Infections

• Main Authors: Pratik Bhagunde (Author), Parul Patel (Author), Mallika Lala (Author), Kenny Watson (Author), William Copalu (Author), Ming Xu (Author), Pooja Kulkarni (Author), Katherine Young (Author), Matthew L. Rizk (Author)
• Format: Book
• Published: Wiley, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Relebactam is a small‐molecule β‐lactamase inhibitor developed as a fixed‐dose combination with imipenem/cilastatin. The pharmacokinetics of relebactam and imipenem across 10 clinical studies were analyzed using data from adult healthy volunteers and patients with bacterial infections. Renal functio...