Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication.

• Principais autores: Melanie McFarlane (Autor), Camilo Arias-Goeta (Autor), Estelle Martin (Autor), Zoe O'Hara (Autor), Aleksei Lulla (Autor), Laurence Mousson (Autor), Stephanie M Rainey (Autor), Suzana Misbah (Autor), Esther Schnettler (Autor), Claire L Donald (Autor), Andres Merits (Autor), Alain Kohl (Autor), Anna-Bella Failloux (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2014-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Replication of arboviruses in their arthropod vectors is controlled by innate immune responses. The RNA sequence-specific break down mechanism, RNA interference (RNAi), has been shown to be an important innate antiviral response in mosquitoes. In addition, immune signaling pathways have been reporte...