Effect of Span 20 Feeding Zone in the Twin Screw Extruder on the Properties of Amorphous Solid Dispersion of Ritonavir

• Main Authors: Hengqian Wu (Author), Zhengping Wang (Author), Yanna Zhao (Author), Yan Gao (Author), Heng Zhang (Author), Lili Wang (Author), Zhe Wang (Author), Jun Han (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A ternary amorphous solid dispersion (ASD) system consisting of drug/polymer/surfactant is receiving increased attention to improve the oral bioavailability of poorly water-soluble drugs. The effect of polymers has been extensively studied, while the impact of surfactants has not yet to be studied t...