Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats

• Main Authors: Bethany P. Cummings (Author), Ahmed Bettaieb (Author), James L. Graham (Author), Jaehyoung Kim (Author), Fangrui Ma (Author), Noreene Shibata (Author), Kimber L. Stanhope (Author), Cecilia Giulivi (Author), Frederik Hansen (Author), Jacob Jelsing (Author), Niels Vrang (Author), Mark Kowala (Author), Michael L. Chouinard (Author), Fawaz G. Haj (Author), Peter J. Havel (Author)
• Format: Book
• Published: The Company of Biologists, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Post-operative increases in circulating bile acids have been suggested to contribute to the metabolic benefits of bariatric surgery; however, their mechanistic contributions remain undefined. We have previously reported that ileal interposition (IT) surgery delays the onset of type 2 diabete...