The Protective Effect of a Newly Developed Molecular Chaperone- Inducer Against Mouse Ischemic Acute Kidney Injury

• Main Authors: Worapat Prachasilchai (Author), Hiroko Sonoda (Author), Naoko Yokota-Ikeda (Author), Katsuaki Ito (Author), Takashi Kudo (Author), Kazunori Imaizumi (Author), Masahiro Ikeda (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activation of the unfolded protein response (UPR) has been suggested to attenuate renal ischemia-reperfusion (I/R) injury. We recently found a compound, namely BIX, that activated the UPR selectively through the activating transcription factor 6 pathway. This study examined the effect of BIX on rena...