Sepsis-Induced Coagulopathy Phenotype Induced by Oxidized High-Density Lipoprotein Associated with Increased Mortality in Septic-Shock Patients

• Main Authors: Yolanda Prado (Author), Pablo Tapia (Author), Felipe Eltit (Author), Cristian Reyes-Martínez (Author), Carmen G. Feijóo (Author), Felipe M. Llancalahuen (Author), Claudia A. Riedel (Author), Claudio Cabello-Verrugio (Author), Jimmy Stehberg (Author), Felipe Simon (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis syndrome is a highly lethal uncontrolled response to an infection, which is characterized by sepsis-induced coagulopathy (SIC). High-density lipoprotein (HDL) exhibits antithrombotic activity, regulating coagulation in vascular endothelial cells. Sepsis induces the release of several proinfla...