Chitosan Glutamate-Coated Niosomes: A Proposal for Nose-to-Brain Delivery

• Main Authors: Federica Rinaldi (Author), Patrizia N. Hanieh (Author), Lik King Nicholas Chan (Author), Livia Angeloni (Author), Daniele Passeri (Author), Marco Rossi (Author), Julie Tzu-Wen Wang (Author), Anna Imbriano (Author), Maria Carafa (Author), Carlotta Marianecci (Author)
• Format: Book
• Published: MDPI AG, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this in vitro study is to prepare and characterize drug free and pentamidine loaded chitosan glutamate coated niosomes for intranasal drug delivery to reach the brain through intranasal delivery. Mucoadhesive properties and stability testing in various environments were evaluated to exami...