Disrupted Mitochondrial and Metabolic Plasticity Underlie Comorbidity between Age-Related and Degenerative Disorders as Parkinson Disease and Type 2 Diabetes Mellitus

• Main Authors: Diana Luz Juárez-Flores (Author), Mario Ezquerra (Author), ïngrid Gonzàlez-Casacuberta (Author), Aida Ormazabal (Author), Constanza Morén (Author), Eduardo Tolosa (Author), Raquel Fucho (Author), Mariona Guitart-Mampel (Author), Mercedes Casado (Author), Francesc Valldeoriola (Author), Joan de la Torre-Lara (Author), Esteban Muñoz (Author), Ester Tobías (Author), Yaroslau Compta (Author), Francesc Josep García-García (Author), Carmen García-Ruiz (Author), Jose Carlos Fernandez-Checa (Author), Maria José Martí (Author), Josep Maria Grau (Author), Francesc Cardellach (Author), Rafael Artuch (Author), Rubén Fernández-Santiago (Author), Glòria Garrabou (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic Parkinson's disease (iPD) and type 2 diabetes mellitus (T2DM) are chronic, multisystemic, and degenerative diseases associated with aging, with eventual epidemiological co-morbidity and overlap in molecular basis. This study aims to explore if metabolic and mitochondrial alterations...