4-AP-3-MeOH Promotes Structural and Functional Spontaneous Recovery in the Acute Sciatic Nerve Stretch Injury

• Auteurs principaux: Yan Chen (Auteur), Weidong Wang (Auteur), Zhimin Zhao (Auteur), Dong Ren (Auteur), Danmou Xin (Auteur)
• Format: Livre
• Publié: SAGE Publishing, 2020-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: 4-AP-3-MeOH, a derivative of 4-aminopyridine, was developed and demonstrated to prevent nerve pulse diffusion due to myelin damage and significantly enhance axonal conduction following nerve injury. Currently, repurposing the existing drug such as 4-AP-3-MeOH to restore motor function is...