HIF-PH Encoded by <i>EGLN1</i> Is a Potential Therapeutic Target for Chronic Lymphocytic Leukemia

• Main Authors: Wancheng Guo (Author), Daomiao Liang (Author), Peilong Wang (Author), Le Yin (Author), Huifang Zhang (Author), Cheng Xing (Author), Zineng Huang (Author), Yinghua Wu (Author), Heng Li (Author), Zhao Cheng (Author), Xiaojuan Xiao (Author), Jing Liu (Author), Zhihua Wang (Author), Hongling Peng (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Owing to the recent emergence of drug resistance to Bruton's tyrosine kinase inhibitors (BTK) in chronic lymphocytic leukemia (CLL) treatment, it is crucial to identify alternative therapeutic targets. Therefore, we aimed to identify therapeutic options for CLL besides BTK. We identified that H...