Synthesis and Evaluation of Novel ⁶⁸Ga-Labeled [D-Phe⁶,Leu¹³ψThz¹⁴]bombesin(6-14) Analogs for Cancer Imaging with Positron Emission Tomography

• Egile Nagusiak: Lei Wang (Egilea), Chao-Cheng Chen (Egilea), Zhengxing Zhang (Egilea), Hsiou-Ting Kuo (Egilea), Chengcheng Zhang (Egilea), Nadine Colpo (Egilea), Helen Merkens (Egilea), François Bénard (Egilea), Kuo-Shyan Lin (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Gastrin-releasing peptide receptor (GRPR) is overexpressed in various cancers and is a promising target for cancer diagnosis and therapy. However, the high pancreas uptake and/or metabolic instability observed for most reported GRPR-targeted radioligands might limit their clinical applications. Our...