Medication-related osteonecrosis of the jaw using periodontitis-induced rat before tooth extraction

• Main Authors: Kyeong-Mee Park (Author), Jieun Cheong (Author), Nan-Sim Pang (Author), Kee-Deog Kim (Author), Jung-Seok Lee (Author), Wonse Park (Author)
• Format: Book
• Published: BMC, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective This study aimed to investigate the occurrence of medication-related osteonecrosis of the jaw (MRONJ) after tooth extraction due to periodontitis in ovariectomized rats. Methods Twenty-four osteoporosis-induced rats were administered with zoledronic acid (ZA; ZA group) or saline (...