Determination of the Elution Capacity of Dalbavancin in Bone Cements: New Alternative for the Treatment of Biofilm-Related Peri-Prosthetic Joint Infections Based on an <i>In Vitro</i> Study

• Main Authors: Mar Sánchez-Somolinos (Author), Marta Díaz-Navarro (Author), Antonio Benjumea (Author), Marta Tormo (Author), José Matas (Author), Javier Vaquero (Author), Patricia Muñoz (Author), Pablo Sanz-Ruíz (Author), María Guembe (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antibiotic-loaded bone cement is the most widely used approach for the treatment of biofilm-induced septic sequelae in orthopedic surgery. Dalbavancin is a lipoglycopeptide that acts against Gram-positive bacteria and has a long half-life, so we aimed to assess whether it could be a new alternative...