Phaseolus vulgaris extract ameliorates high-fat diet-induced colonic barrier dysfunction and inflammation in mice by regulating peroxisome proliferator-activated receptor expression and butyrate levels

• Main Authors: Carmen Avagliano (Author), Carmen De Caro (Author), Mariarosaria Cuozzo (Author), Fabrizio Maria Liguori (Author), Giovanna La Rana (Author), Laura Micheli (Author), Lorenzo Di Cesare Mannelli (Author), Carla Ghelardini (Author), Orlando Paciello (Author), Roberto Russo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity is a health concern worldwide, and its onset is multifactorial. In addition to metabolic syndrome, a high-fat diet induces many deleterious downstream effects, such as chronic systemic inflammation, a loss of gut barrier integrity, and gut microbial dysbiosis, with a reduction of many butyra...