Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development

• Main Authors: Milica Markovic (Author), Moran Zur (Author), Noa Fine-Shamir (Author), Ester Haimov (Author), Isabel González-Álvarez (Author), Arik Dahan (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The main factors influencing the absorption of orally administered drugs are solubility and permeability, which are location-dependent and may vary along the gastrointestinal tract (GIT). The purpose of this work was to investigate segmental-dependent intestinal absorption and its role in controlled...