Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development

• 主要な著者: Milica Markovic (著者), Moran Zur (著者), Noa Fine-Shamir (著者), Ester Haimov (著者), Isabel González-Álvarez (著者), Arik Dahan (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2020-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The main factors influencing the absorption of orally administered drugs are solubility and permeability, which are location-dependent and may vary along the gastrointestinal tract (GIT). The purpose of this work was to investigate segmental-dependent intestinal absorption and its role in controlled...