Protective Effect of Baccharis trimera Extract on Acute Hepatic Injury in a Model of Inflammation Induced by Acetaminophen

• Main Authors: Bruno da Cruz Pádua (Author), Joamyr Victor Rossoni Júnior (Author), Cíntia Lopes de Brito Magalhães (Author), Míriam Martins Chaves (Author), Marcelo Eustáquio Silva (Author), Maria Lucia Pedrosa (Author), Gustavo Henrique Bianco de Souza (Author), Geraldo Célio Brandão (Author), Ivanildes Vasconcelos Rodrigues (Author), Wanderson Geraldo Lima (Author), Daniela Caldeira Costa (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Acetaminophen (APAP) is a commonly used analgesic and antipyretic. When administered in high doses, APAP is a clinical problem in the US and Europe, often resulting in severe liver injury and potentially acute liver failure. Studies have demonstrated that antioxidants and anti-inflammato...