Are minor alleles more likely to be risk alleles?

Abstract Background Genome-wide association studies (GWASs) have revealed relationships between over 57,000 genetic variants and diseases. However, unlike Mendelian diseases, complex diseases arise from the interplay of multiple genetic and environmental factors. Natural selection has led to a high...

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Main Authors: Takashi Kido (Author), Weronika Sikora-Wohlfeld (Author), Minae Kawashima (Author), Shinichi Kikuchi (Author), Naoyuki Kamatani (Author), Anil Patwardhan (Author), Richard Chen (Author), Marina Sirota (Author), Keiichi Kodama (Author), Dexter Hadley (Author), Atul J. Butte (Author)
Format: Book
Published: BMC, 2018-01-01T00:00:00Z.
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3rd Floor Main Library

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