Liposome-Micelle-Hybrid (LMH) Carriers for Controlled Co-Delivery of 5-FU and Paclitaxel as Chemotherapeutics

• Main Authors: Md. Musfizur Hassan (Author), Bilquis Romana (Author), Guangzhao Mao (Author), Naresh Kumar (Author), Fabio Sonvico (Author), Pall Thordarson (Author), Paul Joyce (Author), Kristen E. Bremmell (Author), Timothy J. Barnes (Author), Clive A. Prestidge (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Paclitaxel (PTX) and 5-fluorouracil (5-FU) are clinically relevant chemotherapeutics, but both suffer a range of biopharmaceutical challenges (e.g., either low solubility or permeability and limited controlled release from nanocarriers), which reduces their effectiveness in new medicines. Anticancer...