The ADEM2 project: early pathogenic mechanisms of preschool wheeze and a randomised controlled trial assessing the gain in health and cost-effectiveness by application of the breath test for the diagnosis of asthma in wheezing preschool children

• Main Authors: Sophie Kienhorst (Author), Moniek H. D. van Aarle (Author), Quirijn Jöbsis (Author), Michiel A. G. E. Bannier (Author), Elin T. G. Kersten (Author), Jan Damoiseaux (Author), Onno C. P. van Schayck (Author), Peter J. F. M. Merkus (Author), Gerard H. Koppelman (Author), Frederik-Jan van Schooten (Author), ADEM2 Consortium (Author), Agnieszka Smolinska (Author), Edward Dompeling (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The prevalence of asthma-like symptoms in preschool children is high. Despite numerous efforts, there still is no clinically available diagnostic tool to discriminate asthmatic children from children with transient wheeze at preschool age. This leads to potential overtreatment of...