Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells

• Main Authors: Junqian Zhang (Author), Chunjie Li (Author), Li Zhang (Author), Yongqing Heng (Author), Tong Xu (Author), Yunjing Zhang (Author), Xihui Chen (Author), Robert M Hoffman (Author), Lijun Jia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lung adenocarcinoma is the most common pathological type of lung cancer with poor patient outcomes; therefore, developing novel therapeutic agents is critically needed. Andrographolide (AD), a major active component derived from the traditional Chinese medicine (TCM) Andrographis paniculate, is a po...