Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells

• Principais autores: Junqian Zhang (Autor), Chunjie Li (Autor), Li Zhang (Autor), Yongqing Heng (Autor), Tong Xu (Autor), Yunjing Zhang (Autor), Xihui Chen (Autor), Robert M Hoffman (Autor), Lijun Jia (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Lung adenocarcinoma is the most common pathological type of lung cancer with poor patient outcomes; therefore, developing novel therapeutic agents is critically needed. Andrographolide (AD), a major active component derived from the traditional Chinese medicine (TCM) Andrographis paniculate, is a po...