Clinical Management in Systemic Type Pseudohypoaldosteronism Due to SCNN1B Variant and Literature Review

• Main Authors: Gülin Karacan Küçükali (Author), Semra Çetinkaya (Author), Gaffari Tunç (Author), M. Melek Oğuz (Author), Nurullah Çelik (Author), Kardelen Yağmur Akkaş (Author), Saliha Şenel (Author), Naz Güleray Lafcı (Author), Şenay Savaş Erdeve (Author)
• Format: Book
• Published: Galenos Yayincilik, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Systemic pseudohypoaldosteronism (PHA) is a rare, salt-wasting syndrome that is caused by inactivating variants in genes encoding epithelial sodium channel subunits. Hyponatremia, hyperkalemia, metabolic acidosis, increased aldosterone and renin levels are expected findings in PHA. Clinical manageme...